I received the July 2007 issue of Bank Note Reporter magazine today. In Smythe's ad on page 15 a Dominion Bank $50 1925 in Choice original VF is being offered at US$1750. I was tempted but decided to pass. It's not a rare note per se, but it's certainly rare in original VF+.
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" Buy the very best notes that you can afford and keep them for at least 10 years. " (Richard D. Lockwood, private communication, 1978).