In fact i would say it's value is reduced because it is off centre. At best its worth $20.00 or so.
IMO: Start off by looking at the back of the note. If it is centered, and if the note is as big as any other DF, then yes, it is off-centered & at best worth $20.
If the back of the note is almost as off-centered as the front (in the same orientation), and the note is slightly smaller then another DF-
then the note has been trimmed where it lacks borders. In this case, it wouldn't be worth much more then face.